dsh-synomega

LIMITATIONS

Known limitations

- **A running prediction cannot be interrupted.** Python inference offers no safe cancellation point, so a cancelled call settles immediately and its eventual result is discarded. If an abandoned call has not returned within `hardKillMs`, the worker is killed and restarted. - **Predictions are ranked candidates, not guarantees.** Forward top-1 accuracy is about 0.64 on the benchmark; routes are proposals, not validated procedures. - **The first call downloads a few hundred megabytes.** In air-gapped, metered, or reproducibility-critical environments, pre-fetch with `scripts/setup.mjs` and treat the download as an explicit opt-in. - **The molecule editor is one more download.** Ketcher ships as a 30 MB browser application; it is fetched on first use rather than vendored, so a fresh install pays for it once and an air-gapped one needs `ketcher.url` pointed at a local copy. - **Retrosynthesis is dual-use.** The prompt section defers judgment about hazardous, controlled, or weaponizable targets to the deployment's own safety policy; this plugin does not itself decide what is permissible.